Common use
Antihypertensive drug, antagonist of angiotensin receptors II. It
specifically and irreversibly blocks receptors of angiotensin which
leads to diminishing of biological effects of angiotensin II.
Angiotensin II effects include vasoconstriction and stimulating
influence on excretion of aldosterone and activation of sympathetic
nervous system. As a consequence arterial pressure diminishes and the
heart does not have to work as hard to pump blood. It does not influence
concentration or triglycerides, content of cholesterol, glucose, uric
acid in blood plasma and excretion of uric acid with urine.
Dosage and direction
Initial dose is 150 mg and it can be increased up to 300 mg on
necessity. In some cases as low chloride diet, treatment with certain
diuretics and others initial dose size should be smaller. Avapro is
taken once a day preferably at the same time.
Precautions
It should be administered with kidney or liver failure, congestive
heart failure, after strong vomit or diarrhea and also during
simultaneous treatment with potassium saving diuretics or medications
containing potassium. This drug causes serious harm to unborn baby
(possibly death) if it is administered and used during the last six
months of pregnancy.
Contraindications
Pregnancy, infancy, hypersensitivity to Avapro.
Possible side effect
The most common side effects include diarrhea, abdominal pain or
heartburn. In case you experience allergic reaction to the medication
(fever, difficult breathing, hives) contact your doctor. Avapro can
cause a condition that results in the breakdown of skeletal muscle
tissue and then in kidney failure. Also call your doctor if you have
muscle pain, tenderness, or weakness especially if you also have
vomiting, and dark colored urine, difficult urination.
Drug interaction
No important drug interactions were described for this medication.
At simultaneous intake with potassium-saving diuretics level of
potassium may increased in blood plasma.
Missed dose
Never take a double dose of this medication. If it is almost time of
the next dose just skip the missed portion and continue to take the
medicine according to the schedule.
Overdose
Immediate medical help is needed in case of overdose which symptoms include fast or slow heartbeat, dizziness.
Storage
Tablets should be stored at room temperature, 15-30 C (59-86 F).
Disclaimer
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cover all directions, possible drug integrations, or precautions.
Information at the site cannot be used for self-treatment and
self-diagnosis. Any specific instructions for a particular patient
should be agreed with your health care adviser or doctor in charge of
the case. We disclaim reliability of this information and mistakes it
could contain. We are not responsible for any direct, indirect, special
or other indirect damage as a result of any use of the information on
this site and also for consequences of self-treatment.