Provera contains medroxyprogesterone acetate, female hormone used to
regulate ovulation and menstrual periods. The medication is used to
treat secondary amenorrhea and abnormal uterine bleeding caused by
hormonal imbalance (fibroids, uterine cancer), to reduce the incidence
of endometrial hyperplasia in postmenopausal women.
Dosage and direction
Take 5 or 10 mg of this medication daily for 5 to 10 days. Take
exactly according to recommendations of your doctor. Avoid taking larger
amounts of the medication. Your doctor may administer to start taking
the medication on a certain day of your menses. While you are on Provera
examine your breasts for lumps on a monthly basis. Provera may change
results of certain medical tests. Inform your doctor that you take this
drug.
Precautions
Do not smoke while you take Provera, unless risk of blood clotting
increases. Inform your doctor about conditions you may have as dose
adjustment may be needed: hypertension, heart disease, recent stroke or
heart attack, congestive heart failure, hypercalcinemia, high
cholesterol or triglycerides, recent miscarriage or abortion, severe
pelvic pain, asthma, migraine headaches, epilepsy, a thyroid disorder,
diabetes, kidney disease, lupus, depression.
Contraindications
Do not take this medication if you have hypersensitivity to its
components, pregnant or breastfeed, suffer with a hormone-related cancer
of genitals or mammary gland, abnormal vaginal bleeding that has not
been diagnosed, have liver disease, a history of stroke or blood clot.
Possible side effect
The most frequent side effects of Provera are: headache, dizziness,
irritability, insomnia, drowsiness, fatigue, depression, nausea,
abdominal pain, thrombophlebitis, cerebrovascular disorders,
hypersensitivity nipple breast, galactorrhoea, erosion of the cervix,
dysmenorrhea.
High doses of the medication may produce acne, hirsutism, changes in body weight, moon face, hyperthermia, alopecia.
Allergic reactions such as hives, rash, facial swelling and difficulty breathing are also possible.
Drug interaction
Aminoglutethimide reduces plasma concentrations and reduces
efficiency of Provera. Inform your doctor about all prescribed and
over-the-counter medications, herbal products, vitamins and food
supplements you use.
Missed dose
Never take a double dose of this medication. If it is almost time
of the next dose just skip the missed portion and continue to take the
medicine according to the schedule.
Overdose
Overdose symptoms may be: dizziness, drowsiness, stomach pain,
nausea, vomiting, breast tenderness, or vaginal bleeding. Seek immediate
medical help if you experience the symptoms listed above.
Storage
Store at room temperature between 20-25 C (68-77 F). Store away
from moisture, heat, and sunlight. It is not recommended to store in a
bathroom and places available for children.